Cranbrook Fire and Emergency Services responded to reports of a structural fire on the 1600 block of 2nd Street North.
Two firefighters and two apparatus responded around 7:30 Thursday evening.
The fire had spread to multiple parts of the building by the time emergency crews arrived.
Once on scene, firefighters requested backup, and crews were able to contain the blaze to a single house.
The City said no occupants were inside the home, and report no injuries. The investigation into the cause of the fire is ongoing.